What is Retatrutide?

Retatrutide is a novel synthetic peptide that acts as a triple receptor agonist targeting GIP (glucose-dependent insulinotropic polypeptide), GLP-1 (glucagon-like peptide-1), and glucagon receptors. It represents a new generation of investigational peptides designed to simulate natural hormonal responses involved in glucose metabolism, appetite suppression, and energy balance.

This compound has gained significant attention in preclinical and early clinical research due to its promising effects on body weight reduction, insulin sensitivity improvement, and lipid profile enhancement.

Mechanism of Action Peptide Sciences Retatrutide

Retatrutide binds and activates three key receptors involved in metabolic regulation:

• GIP Receptor Agonism: Enhances insulin secretion and promotes nutrient storage

• GLP-1 Receptor Agonism: Reduces appetite, delays gastric emptying, and supports glucose control

• Glucagon Receptor Agonism: Increases energy expenditure and fat oxidation

This multi-target synergy mimics physiological hormone cascades, offering superior therapeutic potential compared to single-receptor agents.

Key Research Applications

• Obesity and weight management models

• Insulin resistance and Type 2 diabetes research

• Lipid metabolism and liver health

• Hormonal appetite regulation studies

• Comparative peptide therapy evaluations

Laboratory Use Only of Peptide Sciences Retatrutide

Retatrutide 12mg is supplied as a sterile, lyophilized peptide powder, intended strictly for in vitro or laboratory research use. It is not for human consumption, diagnostic use, or therapeutic purposes.

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Product Specifications

• Compound Name: Retatrutide

• Molecular Formula: C₁₈₁H₂₇₇N₄₇O₅₅

• Molecular Weight: ~4020.5 g/mol

• Purity: ≥99% (HPLC verified)

• Appearance: White lyophilized powder

• Quantity: 12mg per vial

• Storage: Store at -20°C; protect from light and moisture

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 Contraindications & Handling Warnings

• For licensed research institutions and professionals only

• Do not inject or consume under any circumstances

• Avoid contact with skin, eyes, or mucous membranes

• Use appropriate PPE (personal protective equipment) when handling

• Dispose of unused material in compliance with local regulations

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Quality Assurance

• Produced in a cGMP-compliant facility in the USA

• Subjected to independent laboratory testing for identity, potency, and purity

• Certificate of Analysis (CoA) available upon request for research verification

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FDA Disclaimer

This product is not approved by the United States Food and Drug Administration (FDA). It is not intended to diagnose, treat, cure, or prevent any disease. It is strictly for research purposes only. Always consult regulatory guidelines before handling investigational peptides.
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